... I couldnt imagine that it would be an all too attractive tourist destination for those that need to prioritize. But it is certainly worth visiting and a great place to live though!
The night-life has changed a bit in downtown HArrisburg in the past 3-4 years with the addition of some clubs and bars (disappearance of some unique personal favorite spots—i.e. the vault, the wyre); good or bad there are more drunken 20somethings out and about raising hell in the streets.
There is also city-island where you can go catch a minor league ball game or soccer game or go for a bike-ride or walk. if you are into camping and hiking, there are lots of trails (e.g. appalachian trail) and parks in the area. there are museums, a movie theatre that plays indie/foreign flics, the forum where you can see/hear the harrisburg symphony or other shows—for that matter there is always live music throughout the week somewhere (e.g. http://www.hbgonline.com/), or if theatre is your thing there are play houses (e.g. gamut) etc, etc.
you can get Indian food and sushi/sashimi among other kinds of food. Harrisburg is also close to Lancaster (Amish country) and Hershey (home of Hershey Chocolate). Philly, Pittsburgh, State College (Penn State), and Baltimore are all with in a 2-3 hours drive too.